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OPRA Exam Sample Paper. Merely understanding the syllabus and preparing for the topic is not enough. For robust OPRA preparation, you must know the format and type of questions you can experience in the exam and prepare as many mock tests and OPRA exam sample papers as possible. Here are a few sample questions that you can get in your OPRA The application process takes 3-4 months, as detailed in the OPRA Application Process document linked below. OPRA applications need to be approved by both the City Commission

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Approach for a patient with a stage II-III ESMO EARLY (GOOD) risk category rectal cancer (cT3a/b in mid- or high rectum, N0 (or also cN1 if high), MRF clear, no EMVI). a. Upfront surgery b. Short course radiotherapy (SCRT) followed by surgery c. Long-course chemoradiotherapy (LCCRT) followed by surgery d. Total Neoadjuvant Therapy (TNT) If choosing a TNT approach, which protocol would you prefer in this case? a. PRODIGE 23 (FOLFIRINOX – LCCRT – Surgery – FOLFOX) b. RAPIDO or STELLAR (SCRT – FOLFOX or CAPOX – Surgery) c. Induction OPRA or CAO/ARO/AIO-12 (FOLFOX – LCCRT – Surgery) d. Consolidation OPRA or CAO/ARO/AIO-12 (LCCRT – FOLFOX – Surgery) Case 2 – Indicate your preferred approach for a patient with an ESMO INTERMEDIATE risk category rectal cancer (cT3a/b if low rectum, levators clear, MRF clear OR cT3a/b in mid- or high rectum, cN1-2 (not extra-nodal), no EMVI). a. Upfront surgery b. Short course radiotherapy (SCRT) followed by surgery c. Long-course chemoradiotherapy (LCCRT) followed by surgery d. Total Neoadjuvant Therapy (TNT) If choosing a TNT approach, which protocol would you prefer in this case? a. PRODIGE 23 (FOLFIRINOX – LCCRT – Surgery – FOLFOX) b. RAPIDO or STELLAR (SCRT – FOLFOX or CAPOX – Surgery) c. Induction OPRA or CAO/ARO/AIO-12 (FOLFOX – LCCRT – Surgery) d. Consolidation OPRA or CAO/ARO/AIO-12 (LCCRT – FOLFOX – Surgery) Case 3 – Indicate your preferred approach for a patient with an ESMO BAD risk category rectal cancer (cT3c/d or very low localisation, levators threatened, MRF clear OR cT3c/d mid-rectum, cN1–N2 (extra-nodal), EMVI + OR limited cT4aN0). a. Upfront surgery b. Short course radiotherapy (SCRT) followed by surgery c. Long-course chemoradiotherapy (LCCRT) followed by surgery d. Total Neoadjuvant Therapy (TNT) If choosing a TNT approach, which protocol would you prefer in this case? a. PRODIGE 23 (FOLFIRINOX – LCCRT – Surgery – FOLFOX) b. RAPIDO or STELLAR (SCRT – FOLFOX or CAPOX – Surgery) c. Induction OPRA or CAO/ARO/AIO-12 (FOLFOX – LCCRT – Surgery) d. Consolidation OPRA or CAO/ARO/AIO-12 (LCCRT – FOLFOX – Surgery) Case 4 – Indicate your preferred approach for a patient with an ESMO

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Of fried dough that can be eaten with sweet or savoury toppings and Galatopita – a milk custard tart.Where to stay in the Mani Peninsula GreeceMani is not the place to come for large scale resort hotels. Rather you’ll find smaller boutique style hotels, guest houses and holiday suites. Many are in older converted buildings but some are in newer buildings. These are required by planning restrictions to be constructed in the traditional Maniot style of stone faced, square tower houses.Hotels in the Outer Mani – Kardamyli to LimeniThe Diapori Suites Hotel where we stayed in Kardamyli is minimalist in style with stunning views, gardens and infinity poolLocated in a restored 18th-century tower, boutique hotel Pirgos Mavromichali overlooks the picturesque bay at LimeniHotels in the Deep Mani – Areopoli to Cape TenaroThe historic Kyrimai Hotel in Gerolimenas offers a luxurious atmosphere and gourmet restaurant by the sea.Located on the sandy beach in Porto Kagio, Akrotiri B&B offers simple rooms behind their sea-view restaurantHotels in the Inner Mani – Cape Tenaro to GythioThe 4-star Las Hotel & Spa in Gythio where we stayed offers contemporary style with roof terrace pool and restaurantHotels in MonemvasiaThe Kinsterna Hotel is a luxurious spa hotel with gourmet restaurant and views of Monemvasia and the Aegean SeaThe stone-built Likinia Hotel is located within the walled town of Monemvasia with views of the Aegean SeaBest time to visit the Mani PeninsulaWe think the best time to visit the Mani peninsula is spring and autumn, if you are planning a road trip like the one we took. The weather in Mani is warm, the days sunny, but there’s not the burning heat of summer that brings everything to a sweaty standstill. Mani Peninsula GreeceFrom May, sunny days are the norm, although in early May you might still have some cloud or the occasional shower. It’s worth knowing that Greek Easter weekend in April / May and the 1st of May are big holidays in Greece. Many Greeks travel during this time, making accommodation harder to find.From mid-May to end June the temperatures are pleasant and the wild flowers blooming. July and August are high season, when temperatures soar and Greek holiday makers descend on Mani. If you want to avoid the crowds wait until September and October. Or, even into November, which are great times to tour the Mani.How to get to the Mani PeninsulaWhere the southern Peloponnese was previously a quiet backwater, the fast toll road from Athens has made it possible to reach Kalamata in under 3 hours. Kalamata is the gateway city for the Mani and you could easily spend a day or two here. The bus to Kalamata from Athens Kifissos bus station has

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Teabo and more towns hail each other as they move from their homes to work and back, or head off for authentic Yucatecan grub just up the block on Mission Street.La gente de Peto, Mamá, Oxkutzcab, Maní, Akíl, Teabo y más pueblos se saludan mientras andan de sus casas al trabajo y viceversa, o se dirigen a la comida yucateca original que está justo arriba en la calle Misión.How do you say "peanuts" in Spanish? - Maní.¿Cómo se dice "peanuts" en español? - Maní.Info Photos Christine Elise Mani hasn't published any photos yet.Info Fotos Christine Elise Mani no ha publicado ninguna foto todavía.They say the name is from Mani, a jewel.Dicen que el nombre es de Mani, una joya.With Niko G4 Mani Coolin and the Money in the World.Con Niko G4, Mani Coolin y el Dinero del Mundo.Info Photos Christine Mani hasn't published any photos yet.Info Fotos Christine Mani no ha publicado ninguna foto todavía.It was built thanks to the legacy of Aaron Mani in 1370.Fue construido con el legado de Aaron Mani en 1370.. OPRA Exam Sample Paper. Merely understanding the syllabus and preparing for the topic is not enough. For robust OPRA preparation, you must know the format and type of questions you can experience in the exam and prepare as many mock tests and OPRA exam sample papers as possible. Here are a few sample questions that you can get in your OPRA

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The latest appliance is purpose-built to reliably handle rising market data volumes and volatility, including the upcoming OPRA feed upgradeSt. Louis, MO— August 23rd, 2023 – Exegy, a leading provider of end-to-end, front-office trading solutions for capital markets, is announcing its next generation ticker plant, purpose-built for processing options market data. This cutting-edge platform can process the OPRA feed on a single 2U server and provides an immediate 2x latency reduction compared to the previous generation.This 6th generation ticker plant is the foundation for future latency improvements and feature updates, continuing its 15+ year history as the ideal, managed market data solution for the industry’s top brokers, trading venues, and global hedge funds.With ever-increasing options trading volumes and the new OPRA feed going live on October 9th, the ability to reliably process growing quantities of market data with consistent, low latency is critically important for the trading community. Exegy’s unique, FPGA-based, managed appliance has scalability that cannot be matched by fully software-based solutions.David Taylor, CEO of Exegy, says: “The sustained volatility in capital markets continues to drive market data volumes to new historic peaks, especially in the US equity options markets. The OPRA consolidated tape doubling its data streams and new options markets coming online imminently further increases the pressure on existing market data infrastructures.”By the end of 2022, US stock options surpassed 10 billion contracts, with single-stock and index options volumes more than doubling since 2019. Now, OPRA’s guidance states that participants should prepare for capacity of 120+ million messages per second following the expansion.Arnaud Derasse, CPO at Exegy, adds: “Trading institutions need to boost capacity regularly with scalable and resilient infrastructure to keep pace with data volumes. This is particularly true for US options trading today. Exegy’s latest generation ticker plant offers the most compact and efficient solution,

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Open Public Records Act (OPRA)To obtain the OPRA Form, CLICK HEREState of New Jersey, Government Records CouncilCommon LawA public record under common law is one required to be kept, or necessary to be kept in discharge of a duty imposed by law, or directed by law to serve as a memorial and evidence of something written, said, or done, or a writing filed in a public office. The elements essential to constitute a public record are that it be a written memorial, that it be made by a public officer, and that the officer be authorized by law to make it.If the information requested is a "public record" under common law and the requester has a legally recognized interest in the subject matter contained in the material, then the material must be disclosed if the individual's right of access outweighs the State's interest in preventing disclosure.Note that any challenge to a denial of a request for records under common law cannot be made to the Government Records Council, as the Government Records Council only has jurisdiction to adjudicate challenges to denials of OPRA requests. A challenge to the denial of access under common law can be made by filing an action in Superior Court.What is the Open Public Records Act (OPRA)? What to do if your request has been denied?If you wish to have copies of any of these records the fees are:· $0.05 per page for letter sized pages and smaller· $0.07 per page for legal sized pages and larger· For delivery, all fees will be based upon the type of delivery requested and the fee will be added to page costs.· Extraordinary service fees are dependent upon the request (i.e. computer disc, CD-ROM, DVD).· Payment may be in the form of cash, check or money order.

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ADVANCED (UGLY) risk category rectal cancer (cT3 with any MRF involved, any cT4a/b, lateral node +). a. Upfront surgery b. Short course radiotherapy (SCRT) followed by surgery c. Long-course chemoradiotherapy (LCCRT) followed by surgery d. Total Neoadjuvant Therapy (TNT) If choosing a TNT approach, which protocol would you prefer in this case? a. PRODIGE 23 (FOLFIRINOX – LCCRT – Surgery – FOLFOX) b. RAPIDO or STELLAR (SCRT – FOLFOX or CAPOX – Surgery) c. Induction OPRA or CAO/ARO/AIO-12 (FOLFOX – LCCRT – Surgery) d. Consolidation OPRA or CAO/ARO/AIO-12 (LCCRT – FOLFOX – Surgery) ResultsOne hundred and seventy delegates attended the AICCC including 17 colorectal surgeons (CRS), 7 radiation oncologists (RO) and 21 medical oncologists (MO). Forty-five participants answered at least one question in the survey. Thirteen were excluded from subsequent analysis as they did not specify their specialty. The response rate was therefore 71%. Data was 95% complete for this group.Early riskSeventy-seven percent (24/31) of all specialists preferred an upfront surgery approach whilst neoadjuvant LCCRT and SCRT were preferred by 10% each (Fig. 3A). CRS and RO almost unanimously chose upfront surgery whereas MO were split between upfront surgery (50%) and a form of neoadjuvant radiation (40%) (p = 0.41) (Fig. 3B). Just one participant selected TNT for early-risk rectal cancer.Fig. 3Preferred treatment approaches to ESMO rectal cancer risk categories, A all participants, B–E by specialistFull size imageIntermediate riskThe greatest heterogeneity of responses was observed in this category. Just over half of respondents (16/30) indicated a preference for TNT whilst a third chose LCCRT as the preferred neoadjuvant strategy. Seven percent of specialists opted for SCRT with another 7% preferring upfront surgery. TNT was selected most prominently by MO (71%) whilst LCCRT was most popular amongst RO (57%) and CRS (44%) (p = 0.30) (Fig. 3C).If utilizing a TNT approach, 55% (17/31) selected a consolidation-type (OPRA or CAO/ARO/AIO-12) regimen, 23% a RAPIDO or STELLAR regimen, 16% PRODIGE-23 and 6% an induction-type (OPRA or CAO/ARO/AIO-12) regimen (Fig. 4A). The majority of CRS and RO preferred a consolidation regimen whilst MO were divided between consolidation (40%) and a RAPIDO or STELLAR regimen

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To downsize the primary tumour to improve surgical margins and provide a route to non-operative management (NOM) in selected patients with a complete clinical response.Recently, multiple clinical trials, such as OPRA, PRODIGE-23 and RAPIDO, have demonstrated the benefits of TNT including an increased rate of clinical (cCR) and pathological complete response (pCR), improved disease-free survival (DFS) and the facilitation of NOM [7,8,9]. Although patient inclusion criteria and TNT regimens differed between the trials, the overall benefits are supported by a meta-analysis of eight studies totaling over 2000 patients [10]. As such, TNT is broadly recommended by the National Comprehensive Cancer Network (NCCN) for > T3 tumours, any node-positive disease or an involved or threatened circumferential margin [11]. On the other hand, the European Society of Medical Oncology (ESMO) rectal cancer guidelines predate the publication of many landmark TNT trials, and therefore, TNT does not feature prominently [12]. Furthermore, not all rectal cancer specialists are proponents of TNT given the lack of longer-term outcome data, especially overall survival (OS), as well as concerns of overtreatment [13, 14].The primary goal of this survey therefore was to determine the TNT preferences of specialists attending the All-Ireland Colorectal Cancer Conference (AICCC) 2022, including the lead investigators of the influential OPRA, PRODIGE-23 and RAPIDO trials.MethodsWe conducted a survey of colorectal surgery (CRS), radiation oncology (RO) and medical oncology (MO) specialists attending the national AICCC, an in-person-only event on 14 October 2022. An overview of the methodology is presented in Fig. 1.Fig. 1Overview of the survey methodologyFull size imagePrior to the survey, conference attendees received a 90-min education session on rectal cancer featuring updates from lead investigators of OPRA, PRODIGE and RAPIDO. In the next session, these speakers formed an expert multidisciplinary panel consisting of 2 colorectal surgeons, 1 radiation oncologist, 3 medical oncologists and a radiologist. The current NCCN, ESMO and ASTRO guidelines were reviewed before 4 rectal cancer cases, including the history, radiology and histopathology that were presented to the panel in front of the live audience. The cases were formulated and agreed beforehand by the conference organizing committee, which consisted of a consultant. OPRA Exam Sample Paper. Merely understanding the syllabus and preparing for the topic is not enough. For robust OPRA preparation, you must know the format and type of questions you can experience in the exam and prepare as many mock tests and OPRA exam sample papers as possible. Here are a few sample questions that you can get in your OPRA The application process takes 3-4 months, as detailed in the OPRA Application Process document linked below. OPRA applications need to be approved by both the City Commission

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With its stark landscape and rocky backbone, the Mani peninsula in the southern Peloponnese region of Greece has a personality of its own. The Taygetos mountains drop steeply down to coves of crystal clear water. On the high ground, stone tower houses keep a watchful eye for invaders from the sea. Read about our delightful road trip around the Mani, starting in Kalamata, looping south around Cape Tenaro and returning via the sea port of Gythio in the east.Life in the Mani PeninsulaWhere is the Mani Peninsula?Map of Mani Peninsula GreeceThings to do in the Mani PeninsulaThe Outer Mani / Exo Mani / Messinian ManiKardamyliStoupaAgios NikolaosOitylo and Neo ItiloLimeniThe Deep Mani / Mesa ManiAreopoliDiros cavesGerolimenasVathiaCape TenaroPorto KagioThe Inner Mani / Kato ManiGythioMore places to visit near the Mani peninsulaMonemvasiaMystrasFood in the Mani PeninsulaWhere to stay in the Mani Peninsula GreeceBest time to visit the Mani PeninsulaHow to get to the Mani PeninsulaGetting around the Mani PeninsulaSustainable travel in the Mani PeninsulaMap of Mani Peninsula showing places to visitRead NextMore articles to read about GreecePlan your trip to the Peloponnese in GreecePin itNever miss an update! – Subscribe to receive our latest articles and newsletterLife in the Mani PeninsulaIn past centuries, life in the Mani Peninsula of Greece, governed by strong family clans, who were known for their blood feuds that sometimes lasted generations. But the independent spirit of the Maniots was also shown in their determination to resist Ottoman occupation. Unusually, they negotiated their own self-government through local Beys or rulers. There’s local pride that the flag of revolt in the Greek War of Independence of 1821 was first raised in the Mani, and taken to Kalamata where the Ottoman garrison was overthrown. This article may contain affiliate links that provide commission on purchases you make at no extra cost to you. As an Amazon Associate I earn from qualifying purchases.Kardamyli Mani Peloponnese GreeceWhere is the Mani Peninsula?The most southerly part of mainland Greece, the Peloponnese stretches three fingers southwards towards Crete and the coast of North Africa beyond. Of these three peninsulas, the Mani is the middle one, split between the administrative regions of Messinia to the east and Laconia to the west. This is as far south in Greece as you can go without hitting the coast of Africa. A spine of the Taygetos mountains runs down its centre, giving the Mani a wild and rugged landscape, with fortified tower houses clustered in hilltop villages. Until the 1970s many parts of the Mani were only accessible by boat or stone kaldarimi paths that connected villages. But these days the gateway town of Kalamata receives international flights and there’s a fast road from Athens that makes the Mani much

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=G$141J146 & J147 = the number of days to the proposed expiration date:J146 & J147: =IF(NOW()>=I146+”15:00:00″,”Expired”,DATEDIF(TODAY(),I146,”d”))D145 = one Standard Deviation below the current value of the underlying asset. My Short-Strike must be this value or less.D145 =L145-(L145*T147*SQRT(J146/365)) (assuming a put spread). (see post “Entry Rules for a Vertical Bull Put Credit Spread” for details on how to calculate SD.)D149 = Strike’s delta difference as shown on the Option Chain (the difference from one Strike to the next). For DIA there is a 5-point difference between Strikes.D149: 5D146 = the suggested Short Strike based upon my Entry Rules for a Vertical Bull Put Credit Spread. This is a calculated value using the “FLOOR” function of Excel:D146: =FLOOR(D145,D149)+E148D147 = the suggested Long Strike.D147: =D146+D142Create OPRA Code NameE146 = the OPRA code for the calculated Short Strike Put Option:E146: =IF(D146=””,””,”.”&E145&TEXT(I146,”YYMMDD”)&LEFT(B146,1)&D146)E147 = the OPRA code for the calculated Long Strike Put OptionE147: =IF(D147=””,””,”.”&E145&TEXT(I147,”YYMMDD”)&LEFT(B147,1)&D147)I can now use these OPRA IDs with ToS to pull options-specific data for the rest of my subsections. Performance Data For My Prospective SpreadThis subsection will show how to:Calculate the Mark Premium Price for the Vertical Spread.Display the Probability the Short Strike will expire Out-of-The-Money (OTM).Display the Probability the asset value will “touch” the Short Strike.Display the percentage the underlying asset have to fall before going ITM with the Short StrikeDisplay the Implied Volatility (IV) of the underlying asset.Retrieve the Current Asset PriceL145 = The current price of the Spreads’ underlying assetL145: =IF(E145=””,””,RTD(“tos.rtd”,,”LAST”,E145))Get the Spread’s Premium price:M146 = the Bid price of the Short-Strike leg. This will be a positive value =IF($E146=””,””,RTD(“tos.rtd”,,”BID”,$E146)*IF(C146>0,-1,1))M147 = the Bid price of the Long-Strike leg. This will be a negative value.M147: =IF($E147=””,””,RTD(“tos.rtd”,,”BID”,$E147)*IF(C147>0,-1,1))O146 = the Ask price of the Short-Strike leg. This will be a positive valueO146: =IF($E146=””,””,RTD(“tos.rtd”,,”ASK”,$E146)*IF(C146>0,-1,1))O147 = the Ask price of the Long-Strike leg. This. OPRA Exam Sample Paper. Merely understanding the syllabus and preparing for the topic is not enough. For robust OPRA preparation, you must know the format and type of questions you can experience in the exam and prepare as many mock tests and OPRA exam sample papers as possible. Here are a few sample questions that you can get in your OPRA

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Up at a supermarket, get to a bank or purchase a few local souvenirs, this is the place to get your business done.Gythio Peloponnese Greece The town offers several squares where the locals stop for a chat, a harbour front lined with cafes. There’s a marina where yachts making a trip around the Ionian side of Greece often stop.A cluster of fish tavernas, with racks of octopus drying outside, are a good place to taste some of the locally caught seafood. But there are numerous places to eat, from back street old man cafes to trendy spots to sip a frappé. Kranai – Marathonisi near Gythio Mani Peninsula Greece Kranae near GythioA short walk from the harbour is the pretty islet of Kranae or Marathonisi, accessed by a causeway. In Ancient Greek mythology, it’s the place where Paris and Helen of Troy spent their first night after fleeing from Sparta. Kranai – Marathonisi near Gythio Mani Peninsula Greece Kranai – Marathonisi near Gythio Mani Peninsula Greece If you take a walk there you can see the lighthouse that protects the entrance to Gythio harbour. There’s a small chapel and the fortified tower built by Tzannetakis Grigorakis. He was one of the leaders of the Greek War of Independence. It’s now a Museum of Mani, but was closed when we visited.Gythio Peloponnese GreeceGythio’s two and three story houses are stacked up the lower slopes of the wooded hill, with the square Mani look about them. But the pastel shades rather than stone walls give them a softer and more cosmopolitan look than the villages of Deep Mani. Gythio Peloponnese GreeceWe wandered up the hill among these older houses, through the stepped alleyways with their neat flowering pots. Our reward was views back towards the harbour. There’s also an ancient theatre with stone semicircle of seats. The gate was shut so we waded through the grass for a photograph.Ancient theatre at Gythio Peloponnese Greece Beaches near GythioWhile there’s no town beach, the long stretch of golden sand at Mavrovouni is only just south of Gythio. To the north are several more pretty beaches and coves. Driving northwards along the coast, look out for the rusty but photogenic “Demetrios” shipwreck on Valtaki beach, This is a nice place to relax with a beachside restaurant.Dimitrios Shipwreck near Gythio Mani Peninsula Greece We used Gythio as our base for a couple of days, staying in the town at the modern and stylish Las Hotel and Spa. This 4 star hotel offers contemporary rooms and a rooftop pool with 360 roofgarden bar and restaurant. This offers panoramic views of the town, not to mention some excellent cocktails and dining. Read my review of Las Hotel and